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R65.11 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction


The ICD 10 Code for Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction is listed as R65.11.
Additional information concerning this code and description can be found below including ICD 9 crosswalks / GEMS, chapter information, and DRGs where available.

ICD 10 CM Field Value
Diagnosis Code: R65.11
Description: Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
  • Use additional code to identify specific acute organ dysfunction, such as:
  • acute kidney failure (N17.-)
  • acute respiratory failure (J96.0-)
  • critical illness myopathy (G72.81)
  • critical illness polyneuropathy (G62.81)
  • disseminated intravascular coagulopathy [DIC] (D65)
  • encephalopathy (metabolic) (septic) (G93.41)
  • hepatic failure (K72.0-)
Diagnostic Related Groups
(MS-DRG v30.0)
870 - Septicemia Or Severe Sepsis W Mv 96+ Hours
871 - Septicemia Or Severe Sepsis W/o Mv 96+ Hours W Mcc
872 - Septicemia Or Severe Sepsis W/o Mv 96+ Hours W/o Mcc
Chapter Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
Block General symptoms and signs (R50-R69)
Parent R65.1 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin
ICD-9-CM Diagnosis Codes General Equivalence Mappings (GEMS):
ICD 9 Dx Code: 995.94 - Systemic inflammatory response syndrome due to noninfectious process with acute organ dysfunction
ICD-10-CM Siblings (same level / similar specificity) of R65.11:
R65.10 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction