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R65.1 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin


The ICD 10 Code for Systemic inflammatory response syndrome (SIRS) of non-infectious origin is listed as R65.1.
Additional information concerning this code and description can be found below including ICD 9 crosswalks / GEMS, chapter information, and DRGs where available.

ICD 10 CM Field Value
Diagnosis Code: R65.1
Description: Systemic inflammatory response syndrome (SIRS) of non-infectious origin
  • Code first underlying condition, such as:
  • heatstroke (T67.0)
  • injury and trauma (S00-T88)
  • Excludes1: sepsis -code to infection
  • severe sepsis (R65.2)
Chapter Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
Block General symptoms and signs (R50-R69)
Parent R65 - Symptoms and signs specifically associated with systemic inflammation and infection
ICD-10-CM Children (deeper level / typically more specific) of R65.1:
R65.10 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction
R65.11 - Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
ICD-10-CM Siblings (same level / similar specificity) of R65.1:
R65.2 - Severe sepsis